Endocrine Abstracts

Aim: To assess efficacy of training and achievement of therapy targets in children and adolescents with type 1 diabetes mellitus in ‘Diabetes Schools’.Materials and methods: The 5-day training course was conducted in ‘Type 1 Diabetes School’ at the Center for the Scientific and Clinical Study of Endocrinology, Uzbekistan Public Health Ministry (Tashkent). The training was conducted by means of a structured program containing all appro...

Aim: To assess level of knowledge and compensation degree in children and adolescents with type 1 diabetes mellitus in “Type 1 Diabetes School”.Materials and methods: The 5-day training course was conducted in ‘Type 1 Diabetes School’ at the Center for the Scientific and Clinical Study of Endocrinology. The training was conducted by means of a structured program containing all appropriate sections. In total 137 children and adolescent...

Background and aims: Progradient course of diabetes mellitus as well as inevitable onset and progression of its late complications having polyorganic character, causing polymorbidity and high mortality of the patients underlie medical–social significance of the problem.Materials and methods: We examined 784 persons (36% men and 64% women, mean age 53 and 51 years respectively) at high risk of diabetes mellitus onset and progression being screened in...

Background: Education is a basic component – to assess achievement of compensation in children and adolescents with type 1 diabetes mellitus within a 3-year period after training.Aim: The work was initiated to assess level of knowledge and compensation degree in children and adolescents with type 1 diabetes mellitus in ‘Type 1 Diabetes School’.Materials and methods: A five-day training course was conducted in ‘T...

Relevance: The main risk factors for developing diabetes type 2, such as obesity, overeating and a sedentary lifestyle are common to a variety of chronic non-infectious diseases.Purpose of the study: Investigate the source of epidemiological indicators, risk factors for type 2 diabetes based on cross-sectional study of the population of Almaty city and Almaty region of Kazakhstan.Methodology: The material for the research were popu...

The work was initiated to comparatively study pregnancy outcomes in patients with type I diabetes mellitus (DMI) with self-control skills and without them.We examined 50 patients with DMI aged from 20 to 29 (mean age 24±3.2 years) ranging from those with newly diagnosed disease to those with DMI duration under 12 years. Glycemia and HBA1c levels were measured to assess carbohydrate metabolism.40 patients with planned pregnancy...

The work was initiated to study peculiarities of pregnancy in patients with prepubertal onset of type 1 diabetes mellitus (T1DM).We examined 22 patients with prepubertal onset of T1DM. Glycemia and HbA1c levels were measured to assess carbohydrate metabolism. All patients were examined in compliance with protocol of management for patients with pre-gestational diabetes.Mean age of the examinees, primagravidas, was 21.4±4.7, th...

Introduction: As were previously shown the erythrocytes glucose uptake is impaired in patients with the Diabetes Mellitus, obesity and polycystic ovarian syndrome due to insulin resistance. For further, study whether the erythrocytes glucose uptake will be impaired in rats with experimental metabolic syndrome were observed gradually.Material and methods: The 40 adult white male rats separated into 4 groups. In 10 rats diabetes were induced by injection o...

The work was initiated to assess basic level of knowledge on essential concepts of type I diabetes mellitus among nurses employed at regional dispensaries of Uzbekistan.We tested 194 nurses employed at the endocrinologist’s offices and regional endocrinological dispensaries to assess level of knowledge on essential concepts of type I diabetes mellitus by means of a 20 question test made up under a 5-day training program in the School of Diabetes.</p...

Sphingolipids constitute the structural base for all types of biological membranes, and are numerous in human and animal tissues. Metabolites of sphingolipids act as biological effectors, modulators and mediators in a number of biochemical processes; they are known to be pathogens in various human pathologies.We aimed at studying activity of sphingomyelinase, concentrations of sphingomyelin and its metabolites, such as ceramide and sphingosine, in organs...